Hi Matt,
Have you explored the entire Settings menu inside Discord yet?
I know there are a lot of settings, and that there’s a section called Voice & Video, with options allowing you to select your input and output devices, activate Krisp noise suppression, as well as an Attenuation option which can decrease the volume of other applications (among others).
See:
https://www.howtogeek.com/663414/how-to-configure-your-microphone-and-headset-in-discord/
Or Discord’s own troubleshooting pages:
https://support.discord.com/hc/en-us/articles/360045138471-Discord-Voice-and-Video-Troubleshooting-Guide
Also, most web browsers have locations where you can change the permissions for access by other applications and devices.
In Chrome, the extended version of these site-specific permissions can be opened by clicking the “Site settings” cogwheel at the bottom of the window shown below, and the general version is located under:
Settings > Privacy and security > Site settings.
Let me know if this helped (or not)!